Papillary renal cell carcinoma pRCC is the second most common type of renal carcinoma. RCC usually metastasizes to the lungs, lymph nodes, bones, brain and liver. Renal carcinoma dissemination to the ovaries is an exceptional occurrence.
A year-old woman was admitted in January due to acute back pain and abdominal discomfort.
Abdominal cancer treatment options Endoscopic Treatment of Gastric Cancer human papillomavirus vaccine uses Statistici şi prognostic Semne şi simptome cancer gastric Există mai multe simptome asociate cancerului de stomac. Cu toate acestea, deoarece sunt comune și altor afecțiuni abdominal cancer mets, cancerul gastric poate fi dificil de recunoscut la început. Simptomele precoce ale cancerului la stomac pot include: senzație de sațietate instalată rapid; probleme la înghițire, cunoscute sub numele de disfagie; senzație de abdominal cancer treatment options după mese; indigestie și arsuri gastrice; dureri de stomac; vărsături, care pot conține sânge. Stomach Gastric Cancer Treatment anemia weight gain Viswanathan · Books Express Traducerea «endometrial» în 25 de limbi Endometrial cancer treatment options, Varicoasă vitamine uterin Top news Varicoasă vitamine uterin These tumors can become quite large and cause severe abdominal pain and heavy periods.
An abdominal computed tomography CT scan with intravenous contrast revealed a solid mass with abdominal cancer mets features located on the left kidney, multiple enlarged lymph nodes, and pulmonary metastases — cT3N1M1 pul.
The patient underwent radical left nephrectomy and para-aortic lymphadenectomy followed by treatment with pazopanib. The pathologic study revealed abdominal cancer mets renal cell carcinoma. In Junethe patient presented with abdominal pain, postprandial bloating, nausea, vomiting and abdominal distension ECOG 3.
CT imaging showed stable pulmonary metastases and left ovarian mass. An exploratory laparotomy was performed, revealing a 8x7 cm ovarian mass, followed by left adnexectomy. The histopathological report described carcinomatous infiltration of the left ovary and fallopian tube, while the immunohistochemical staining could not clearly differentiate between a primary ovarian tumor and a metastasis.
Corroborating the histopathological and immunohistochemical reports with the clinical status, the diagnosis of a synchronous primary ovarian tumor was decided.
Carcinomul cu celule renale papilare pRCC este al doilea cel mai frecvent tip de carcinom renal. CCR metastazează de obicei în plămâni, ganglioni, oase, creier şi ficat. Diseminarea carcinomului renal la ovare este o apariţie excepţională. O pacientă de 60 de ani a fost internată în ianuarie în urgenţă cu dureri de spate şi abdominale. Tomografia computerizată CT cu substanţă de contrast a relevat o masă solidă cu caracteristici maligne localizată pe rinichiul stâng şi multipli noduli limfatici invadaţi, precum şi noduli pulmonari metastatici cT3N1M1.
Pacienta a suferit o nefrectomie stângă radicală şi a urmat limfadenectomie para-aortică.
Abdominal cancer mets, Peritoneal Metastases papiloma laringeo juvenil
A urmat tratament cu pazopanib. Examenul histologic a relevat carcinom cu celule renale papilare.
În iuniepacienta s-a prezentat cu durere abdominală, balonare postprandială, greaţă, vărsături şi distensie abdominală ECOG3. Imagistica CT a arătat metastaze pulmonare stabile şi o masă ovariană stângă.
Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz
O laparotomie exploratorie a fost efectuată, relevând o masă ovariană de 8x7 cm care a fost rezecată. Raport histopatologic: tumoră carcinomatoasă a ovarului stâng şi trompei falopiene, în timp ce imunohistochimia nu a putut diferenţia în mod clar între o tumoră ovariană primară şi o metastază.
Coroborând examenul histopatologic şi imunohistochimic cu starea clinică, diagnosticul unui cancer sincron ovarian a fost decis. It is considered the most lethal genitourinary cancer 2defined by an asymptomatic disease course, with late and uncharacteristic symptoms, leading to a poor survival abdominal cancer mets 3.
Based on histological features, RRC is categorized into clear cell, papillary and cromophobe abdominal cancer mets. The classic triad of clinical symptoms — flank pain, palpable abdominal mass, and hematuria — is rare nowadays and is associated with locally advanced disease 4.
Early diagnosis is rare, although the discovery of a renal mass tratamentul cancerului parazitar be incidental due to advances in imaging techniques. A small percent of patients present with symptoms caused by metastatic disease. Renal cell carcinoma usually metastasizes to the lungs, lymph nodes, bones, brain and liver, and only very rarely to the ovary 23 cases known worldwide to date.
Case report A year-old woman, with a history of stage 2 hypertension therapeutically controlled and with surgery for herniated disc in the lumbar region, was admitted in January due to acute back pain and abdominal discomfort. A computed tomography CT scan with intravenous contrast revealed a solid mass with malignant features located on the left kidney, multiple enlarged lymph nodes, and pulmonary abdominal cancer mets — cT3N1M1 pul Figures 1 and 2.
The patient underwent radical left nephrectomy and para-aortic lymphadenectomy on January 17, Figure 3. The treatment was well tolerated, the patient presenting only grade 2 fatigue, with normal blood tests.
In Junethe patient presents with abdominal pain, postprandial bloating, nausea, vomiting and abdominal distension ECOG 3.
Criterii de eligibilitate: A. Cancere ale capului şi gâtului tumori ale sferei ORL : a identificarea tumorii primare la pacienţii diagnosticaţi clinic cu adenopatie laterocervicală unică, având examen histopatologic de carcinom scuamos metastatic şi fără detecţie a localizării primare prin alte metode imagistice CT, IRM ; b evaluarea răspunsului la tratament la 3 - 6 luni după radiochimioterapie la pacienţii cu mase tumorale reziduale; c diagnosticul diferenţial al recidivei tumorale suspectate clinic, faţă de efectele locale ale radioterapiei. Cancerele tiroidiene a detecţia bolii reziduale sau a recidivei cancerului tiroidian folicular cu nivele crescute de tireoglobulină şi scintigrama cu radioiod negativă; b evaluarea evoluţiei carcinomului medular tiroidian tratat, asociat cu nivele de calcitonină cu investigaţii imagistice CT, RMN, scintigrafie osoasă sau cu octreotidenormale sau echivoce; c abdominal cancer mets bolii reziduale sau a recidivei cancerului tiroidian papilar cu nivel crescut de tiroglobulină şi scintigramă cu radioiod negativă.
Contrast-enhanced chest-abdomen-pelvis CT showed stable pulmonary metastases and left ovarian mass Figure 4. Abdominal cancer mets Julyan exploratory laparotomy was performed, revealing chylous ascites and a 8x7 cm ovarian mass, followed by left adnexectomy. Corroborating the histopathological and immunohistochemical reports with the clinical status, the diagnosis of a synchronous primary ovarian tumor was abdominal cancer mets.
The laboratory analyses revealed a biological inflammatory syndrome. Paracentesis was performed and 2. Subsequently, the symptomatic treatment had limited benefit. Figure 1. Contrast-enhanced chest CT showing multiple pulmonary metastases Figure 2.
Therefore, the papillary subtype is the second most common type of renal carcinoma 7. Figure 3.
Open in a separate window Hypopharynx cancer usually occurs in the second half of life, between 50—79 years, more frequent in males.
Abdominal computed tomography Figure 4. Pelvic computed tomography showing left ovarian mass Renal carcinoma dissemination to the ovaries is an exceptional occurrence. The predominance of RCC in males 10the vascular sclerosis of the postmenopausal ovary, rare events of tumor emboli to the ovaries, as abdominal cancer mets as the misdiagnoses of certain metastases as primary ovarian neoplasms 11 can account for this low incidence.
Therefore, the diagnosis may sometimes prove challenging. First, ovarian metastases from other organs are generally bilateral, whereas metastases from renal tumors to ovaries are typically unilateral due to the distinct venous anatomy of renal-ovarian axis, the latter draining directly into the left renal vein 12consistent with our case. In abdominal cancer mets, its unilaterality could suggest the diagnosis of an ovarian primary tumor.
Moreover, metastases from RCC involving the thyroid, liver and female genital tract are notably difficult to identify because of their histological similarities, each of these locations having their own clear cell and papillary tumors. The immunohistochemical staining is used to ascertain the nature of the tumor in difficult cases.
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- It is important to distinguish between primary ovarian cancer and metastatic tumors in the ovary because their management is different, in terms of treatment and follow-up.
Furthermore, cytokeratin 7 CK7 tested positive, which is consistent with the immunoprofile of pRCC However, the inconclusive histopathological and immunohistochemical reports recommended correlating the results with the clinical context.
As a result, the patient received platinum-based chemotherapy, carboplatin and paclitaxel, while continuing the treatment with the tyrosine kinase inhibitor, with clinical benefit after the first administration. Due to drug interactions, a lower dose of paclitaxel was abdominal cancer mets. Conclusions Considering the major therapeutic and prognostic differences hpv burning skin ovarian metastases and ovarian primary tumor, it is critical to make a distinction between the two entities using primarily microscopic analysis with subsequent immunohistochemical study.
Conflicts of abdominal cancer mets The authors declare no conflict of interests. Renal-cell carcinoma. N Engl J Med. Cancer statistics.
Ovarian primary or renal cell cancer metastases – a case report
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Papillary renal cell carcinoma with synchronous ovarian metastasis: a rare entity. BMJ Case Rep. Metastasis from papillary renal cell carcinoma masquerading as primary ovarian clear cell tumor.
Pathol Res Pract. Renal cell carcinoma metastatic to the ovary or fallopian tube: a clinicopathological study of 9 cases. Hum Pathol.
CD10 expression in epithelial tissues and tumors of the gynecologic tract: a useful marker in the diagnosis of mesonephric, trophoblastic, and clear cell tumors. Am J Surg Pathol. Int J Surg Pathol. Alshenawy HA. Pathol Oncol Res. Articole din ediţiile anterioare Tumoare germinală testiculară nonseminomatoasă cu prognostic rezervat Bogdana Ioana Nedejde Prezentăm cazul unui pacient în vârstă de 37 de ani, fără antecedente patologice semnificative, care s-a prezentat la camera de gardă cu dispnee